Centrafuse 4 stops loading and hangs at the "Configuring speech recognition…" start up message. This affected all users running a non-US English version of Windows 7.
This was resolved with 4.0.26 build of Centrafuse. Please refer to this forum post for more information and how to get the latest version: http://forums.fluxmedia.net/release-information/15312-4-0-26-patch-available.html#post106308
Or try the latest 4.x version.